The study deals with the development of the neocortex in an individual since the time of zygote formation and its unique and very personal development under the effect and strict control of miasms, genetic factors as well as environmental stimuli. The whole constitution thus formed is a peculiar one and has its characteristics with its sole temperament. Since no two neocortexs are alike, the mental and physical attributes of every individual are different hence no two persons are possibly identical. This fact supports the philosophy of Homoeopathy which has a holistic approach and advocates the theory of individualization.