In their lifetime of friendship, kindred spirits Star (Kristen Wiig) and Barb (Annie Mumolo) remained at one another's side through the challenges and triumphs of life. Yet as middle-age approaches, both women feel the inexplicable urge to explore the world. Armed with their signature exuberance, Barb and Star leave their rural Midwestern town behind to embark on a holiday, their first beyond the confines of their community. Directed by Josh Greenbaum; co-starring Jamie Dornan and Damon Wayans Jr.