This volume seeks to enable the discovery of tools in chemical biology by providing readers with various techniques ranging from initial chemical genetic screening to target identification. To successfully highlight the essential components of the chemical biology tool discovery process, the book is organizes into four parts that focus on platforms for molecular discovery in
in vitro
cellular systems,
in vivo
chemical genetic screening prools, and methods used to discover functional protein targets. Written in the highly successful
Methods of Molecular Biology
series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory prools, and key tips on troubleshooting and avoiding known pitfalls.
Practical and informative,
Chemical Biology: Methods and Prools
seeks to improve the success rate of the chemical biology field through the dissemination of detailed and experiential knowledge.