The articles contributed to conference proceedings of 'Advanced Research in Chemical Sciences (ARCS)' have elaborated the advanced research on cross-cutting thematic areas of the conference such as organic synthesis, medicinal chemistry, sustainable chemistry, environmental remediation and renewable energy technology, nanomaterials, liquid-crystalline materials and polymers, computational chemistry, and advanced materials. A high throughput scientific deliberation has been instilled on the recent perspective, scientific achievements, and breakthrough to deal with major challenges in healthcare, energy, environment, and climate change for the greatest benefit of humankind.