Christian Schwarzkopf has developed a new more holistic entrepreneurial ecosystem on a national level and has analyzed as well as compared the fundamentals of innovation and entrepreneurship in Germany and the USA in order to derive the key elements for an entrepreneurial ecosystem. The described ecosystem consists of four circles and 24 elements, with the entrepreneur in the core. Surrounding essential elements, for example, are risk financing, culture or domestic markets. The author shows the differences between Germany and the USA and provides improvement proposals for nations like Germany.