During his long and continuing scholarly career, Patrick Suppes has contributed significantly both to the sciences and to scientific philosophies. In this volume, an international group of Suppes’s colleagues, collaborators, and students seeks to build upon Suppes’s insights. Each of their essays is accompanied by a response from Suppes himself, which together create a uniquely engaging dialogue. Suppes and his peers explore a diverse array of topics including the relationship between science and philosophy; the philosophy of physics; problems in the foundations of mathematics; theory of measurement, decision theory, and probability; the foundations of economics and political theory; psychology, language, and the philosophy of language; Suppes’s most recent research in neurobiology; and the alignment (or misalignment) of method and policy.