Distinguished scientists provide an overview of the molecular pathology of human disease. Each chapter provides an analysis of the molecular biological approaches to individual diseases, such as leukaemia, cardiovascular disease and cancer. To celebrate the formation of the new Department a I-day meeting entitled 'From Genetics to Gene Therapy' was held on 14 December 1992, at which a large audience was inspired by talks from a variety of distinguished speakers. This volume is based on the meeting and contains contributions provided by the invited speakers.