Contents: B. Alcaide—P. Almendros: Novel Aspects on the Preparation of Spirocyclic and Fused Unsual β-Lactams.- S.S. Bari—A. Bhalla: Spirocyclic β-Lactams: Synthesis and Biological Evaluation of Novel Heterocycles.- L. Troisi—C. Granito—E. Pindinelli: Novel and Recent Synthesis and Applications of β-Lactams.- C. Palomo—M. Oiarbide: β-Lactams Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds.- B. Mandal—P. Ghosh—B. Basu: Recent Approaches Towards Solid Phase Synthesis of β-Lactams.- A.Arrieta—B. Lecea—F.P. Cossio: Computational Studies on the Synthesis of β-Lactams Via [ 2+2] Thermal Cycloadditions.- B. K. Banik—I. Banik—F. F. Becker: Novel Anticancer β-Lactams