This book addresses very different subjects from research to practice and from medicine to information technology and medical informatics issues. In most of the European countries, the United States, Canada, Japan and Australia, telemedicine already is one the columns that keep the health care systems under control in terms of cost savings and quality assurance. This is reflected by significant funding from the governments of many of these countries, which are more than ever under a huge pressure of keeping the health care system alive. However, telemedicine has not yet reached mainstream medicine. The interest of scientists to address the issue of impact of telemedicine on the current practice of medicine is still limited. Proper outcomes research on the effectiveness of telemedical applications would strongly fasten the implementation of telemedicine in the current practice of telemedicine. This should make this publication so valid.