The research is aimed at the formation of technologies of healthy lifestyle of the population, taking into account medical and social methods of epidemiological analysis in medical and ecological research of the system 'human health - habitat', based on a set of theoretical, methodological, methodological and practical aspects of the development of the concept of sustainable management of the organisation of systems of medical, ecological and social services, sustainable management of innovation, cluster, investment, on the basis of public-private entrepreneurship.