This book provides a comprehensive overview and critical evaluation of the emerging and exciting topic of interoception – the perception of the body’s internal state. Interest in the topic has been driven by the observation that interoception appears to affect fundamental psychological processes and numerous physical and mental health conditions. In this book, the major authorities in the field present a discussion of the history of interoception, the neural basis of interoception, and the measurement and models of interoception conceptualization. This is followed by a consideration of the many domains that interoception appears to impact (including social and cognitive abilities and mental and physical health conditions) and differences across demographic groups. Interoception: A Comprehensive Guide also explores real world applications, including training for interoception, the modulation of interoception and the impact of such interventions, and future research directions.