After a week of nothing, things are going seriously weird at Maple Ridge Middle School. First, Jamie "Burners" Burns, is asked to be the substitute teacher for the chemistry class, then the class experiments go horribly wrong...and it isn't Mickie's fault. The new man in charge, Principal Morgan, wants to pin the blame on the school's girl genius but Mickie is certain that someone else is behind the whole thing. With only a couple mysterious substances left behind as clues, a strange school-wide computer problem and an alliance with the school's reporter, AJ Harris, do Mickie and Sam have enough to clear Burners once and for all? Can Maple Ridge Middle School's detecting duo prove that there is a different culprit behind the accidents? And catch the real wrong-doer before it's too late?