This book includes selected papers presented at the Indo-French Seminar on Optimization, Variational Analysis and Applications (IFSOVAA-2020), held at the Department of Mathematics, Institute of Science, Banaras Hindu University, Varanasi, India, from 2–4 February 2020. The book discusses current optimization problems and their solutions by using the powerful tool of variational analysis. Topics covered in this volume include set optimization, multiobjective optimization, mathematical programs with complementary, equilibrium, vanishing and switching constraints, copositive optimization, interval-valued optimization, sequential quadratic programming, bound-constrained optimization, variational inequalities, and more. Several applications in different branches of applied mathematics, engineering, economics, finance, and medical sciences have been included. Each chapter not only provides a detailed survey of the topic but also builds systematic theories and suitable algorithms to deduce the most recent findings in literature. This volume appeals to graduate students as well as researchers and practitioners in pure and applied mathematics and related fields that make use of variational analysis in solving optimization problems.