The research program in gamma-ray astronomy focuses on increasing our knowledge of the nature and origin of galactic and extragalactic gamma rays, and understanding high-energy processes in the Sun, celestial objects, interstellar medium, and extragalactic space.This book not only provides an overview of the latest research and future plans for space-borne and ground-based experiments dedicated to the observation of the gamma-ray sky, but also addresses the topic of variable gamma-ray sources from the perspective of their identification and counterparts at different wavelengths. It further gives an overview of the theory related to the most qualified emission processes that take place in these sources and of the nature of their variability.