This book addresses self-injurious behavior (SIB) in individuals with various neurodevelopmental conditions (NDCs). It takes a cross-NDC perspective that synthesizes recent research on variability in incidence and presentation across NDCs and the natural history and neurobiology of SIB. Chapters examine implications for biobehavioral definitions of subtypes of SIB and provide a detailed guide to assessment and intervention using an integrated research-based model for individualized treatment. In addition, chapters present a practice-focused structure using case studies to illustrate clinical implications of research findings. The book concludes with a discussion of current directions in research and their potential to guide innovation in prevention and treatment of SIB. is a must-have resource for researchers, clinicians and practitioners as well as graduate students in the fields of clinical child and school psychology, applied behavior analysis, pediatrics, social work, developmental psychology, behavioral therapy/rehabilitation, child and adolescent psychiatry, clinical psychology and psychiatry of adult intellectual disability, and special education.