This book offers students and instructors the opportunity to analyze businesses whose products and strategies are designed to offer innovative solutions to some of the twenty-first century's most difficult societal challenges. A new generation of profitable businesses is actively engaged in clean tech, renewable energy, and financially successful product system design and supply chain strategies that attempt to meet our economic development aspirations while addressing our social and ecological challenges. This textbook offers background educational materials for instructors and students, business cases illustrating sustainability innovation, and teaching notes that enable instructors to work effectively and accelerate student learning. This text was compiled, edited, and adapted from multiple open source textbooks and created under a Creative Commons License without attribution as requested by the work's original creator or licensee. For a free copy of the e-text, please visit HCIPress.org.