This book is a short and comprehensive study of the best known approaches for preparing the main types of glycosides. It includes synthetic and enzymatic methologies for preparing glycosides of different natures and complexity, many of them currently used as antiviral or antineoplasic drugs. The book is also designed to provide methods for preparing synthetic substrates used for enzymatic detection of glycosidases including those used as substrates for detection of gene markers in plant biotechnology. A chapter providing general strategies employing chemical or enzymatic tools for preparing glycoconjugates - some of which are used as synthetic vaccines - has been incorporated. Special attention is paid to structural characterization, and the book provides the basic tools for structural assignment NMR spectroscopy, X-Ray diffraction, and mass spectrometry techniques.
This book will be indispensable to synthetic organic chemists, biotechnologists, molecular biologists, pharmaceutical chemists, drug designers and those in the pharmaceutical industry, sugar chemists, those interested in natural product synthesis, medicinal chemists, carbohydrate chemists, and those interested in nucleotides or nucleosides. This text provides the necessary elements to those professionals including advanced undergraduates, graduate students, and academics involved in sugar or glycoside chemistry.