The fourth edition of this student-friendly lab manual presents the basic techniques of the organic chemistry laboratory, with an emphasis on doing the work correctly the first time. It is designed to quickly build student proficiency in experimental procedures. New additions include a focus on computer software and hardware and expanded coverage of microscale laboratory equipment to include microscale and ultramicroscale boiling point determination, flash chromatography using Pasteur pipets, and Keck clips used to keep your jointware setups together with possibly fewer clamps.