This volume is divided in six section covering the most experimental approaches involved in the study of the unfolded protein response (UPR) pathway. Chapters detail determination of unfolded protein levels, methods to study UPR signal transmission, analysing the outcomes of the UPR pathway activation, UPR studies in mammalian models, UPR in alternative models, and UPR and disease. Written in the format of the highly successful
Methods in Molecular Biology
series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible prools.
Authoritative and cutting-edge,
The Unfolded Protein Response: Methods and Prools
aims to describe key methods and approaches used in the study of the UPR pathway and its complex cellular implications.
Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.