Variational analysis is a rapidly growing field within pure and applied mathematics, with numerous applications to optimization, control theory, economics, engineering, and other disciplines. This volume brings together state-of-the-art results in variational analysis and its applications, with an emphasis on optimization and control. The included chapters, written by international experts in the field of variational analysis and related topics, are dedicated to Boris S. Mordukhovich, a renowned mathematician, and aim to celebrate his fundamental contributions to variational analysis, generalized differentiation and their applications. This volume is intended for mathematicians studying variational analysis as well as other researchers interested in applying the principles of variational analysis to their area of study.