Hand Wrinkle Patches. Benefits: Smooths lines & wrinkles. Reusable up to 20 times. Can work in hours. Wear day or overnight. Key Ingredients: Nothing but 100% Medical-Grade Silicone. Research Results: A Clinical Evaluation of 92 women in July 2019 found that our Wrinkle Patches assisted with the following:. Smoother Skin: 97.8% experienced smoother skin. Firmer Skin: 90% experienced firmer skin. Rehydration: 92.1% experienced more hydrated skin.