The terror of yellow fever conjures images of mass infection of soldiers during the Spanish-American War and horrific death tolls among workers on the Panama Canal. Medical science has never found a cure and the disease continues to present a threat to the modern world, both as a mosquito-borne epidemic and as a potential biological weapon. Drawing on firsthand accounts and contemporary sources, this book traces the history of the viral infection that has claimed countless victims across the United States, Central America and Africa, and of the global effort to combat this challenging and deadly disease.