This volume constitutes the proceedings of the 18th Industrial Conference on Adances in Data Mining, ICDM 2018, held in New York, NY, USA, in July 2018. The 24 regular papers presented in this book were carefully reviewed and selected from 146 submissions. The topics range from theoretical aspects of data mining to applications of data mining, such as in multimedia data, in marketing, in medicine and agriculture, and in process control, industry, and society.