This book highlights selected papers presented at the 10th International Symposium on Embedded Computing and System Design (ISED) 2021. This symposium provides a platform for researchers to share the latest scientific achievements of embedded computing and system design. The book is divided into three broad sections. The first section discusses topics like VLSI and testing, circuits and systems with a focus on emerging technologies. The second section discusses topics like embedded hardware and software systems and novel applications. The final section discusses the state-of-the-art technologies involving IoT, artificial intelligence, green and edge computing that demonstrates the issues currently.