Lexie and Pippa have been best friends since they met at university, but now their hopes and ambitions are taking them down very different paths.
Lexie, driven to find help for her autistic brother, works for a pharmaceutical giant. Tough, self-sufficient and practical, she has sacrificed personal relationships in her quest for money and influence. In contrast Pippa is an idealistic homeopathic doctor who is driven by her desire to truly care for people. She's devoted to her husband, RAF pilot Oliver, and their young son. She feels more and more alienated from the values of her erstwhile best friend.
Home on leave, Oliver attempts to thaw the frosty relationship between the women. But the chemistry between him and Lexie leads to a night of passion that will change all their fates. And Oliver harbours another, far more shocking secret. When it is revealed, can the broken bonds of love and friendship ever be healed? Or have professional rivalry, bitterness and betrayal fractured those bonds forever?