Eleven-year-old George has a dog, Bart, who seems to know everything about him—from when he is feeling sad to when he will arrive home from school. George's new neighbor and classmate, Lester, also has a dog, Bill Gates, and Lester thinks is the smartest animal in the world. When their teacher assigns a school science project about animal behavior, George and Lester decide to conduct an experiment based on the world-famous Rupert Sheldrake's experiments about dogs. George even has an e-mail exchange with Dr. Sheldrake to help him with the project—and he and Lester soon find out that, through a few simple experiments, kids can make scientific discoveries, too.