This volume provides cutting-edge techniques to further the study chromatin biology. Chapters include both novel and well-established methods for the analysis of DNA-associated proteins, DNA methylation, three-dimensional chromatin interactions, deep sequencing-based tools, and data analysis pipelines. Written in the format of the highly successful
Methods in Molecular Biology
series, each chapter includes an introduction to the topic, provides details of the necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and describes step-by-step, readily reproducible prools.
Authoritative and cutting-edge,
Chromatin: Methods and Prools
aims to further the understanding of how modified DNA and associated proteins affect the transcriptional output of the genome.
Chapter Genome-wide mapping and microscopy visualization of protein-DNA interactions by pA-DamID [Chapter 12] is available open access undera Creative Commons Attribution 4.0 International License via link.springer.com.