The second volume on Dendrimers is again written by pioneers in the field. Their contributions illuminate the aspects of dendrimers mentioned in the subtitle of this volume, and also touch on areas beyond chemistry, namely material sciences as well as biological, medicinal, analytical and nano aspects. Different types of dendrimers (Polyester, POPAM, porphyrin-, podand-, organometallic-, silicon-based) with perfectly or less precisely directed cascade architectures are highlighted. Synthesis, chirality, reactivity, mechanism, host-guest interactions, polymer chemical aspects are addressed. This review is expected to again be most interesting and useful for chemists of all disciplines as well as for neighbouring bio- and material sciences.