This publication presents case studies on the successful application of science, technology, engineering, and mathematics (STEM) education in Thailand, the Republic of Korea, Singapore, and Finland.STEM education has an important role in inclusive and equitable quality education and lifelong learning opportunities for all. By utilizing an inquiry-based and experiential teaching and learning approach as well as integrating engineering and technology with science and mathematics, STEM promotes employability skills, entrepreneurship, and innovation. The case studies in this publication provide inspiration and lessons for ADB developing member countries to enhance their respective STEM education programs.