Fred Figglehorn (Lucas Cruikshank) begins to suspect his new music teacher Mr. Devlin of being a vampire after his original teacher Mrs. Felson vanishes without a trace, and her mysterious replacement sets his sights on the lovely Mrs. Figglehorn. Convinced beyond a doubt that Mr. Devlin intends to put the bite on his unsuspecting friends and neighbors, Fred recruits his father (WWE star John Cena) and his best friends Bertha (Daniella Monet) and Talia (Ariel Winter) to help stop the bloodsucker before he strikes again.