The book exposes the reader to the nature and practice of stereotyping, negative bias, social categorization, modern forms of racism, immigration law empowerment, racialized incarceration, and police brutality in the American heartland. It states that several centuries of white Americans’ negative socializing culture marked by widespread negative attitudes toward African Americans, are not eradicated and are still rife. Further, the book provides a panoramic view of trends of racial discrimination and other negative and desperate challenges that Black, Indigenous, and People of Color face across the world. Finally, the volume examines xenophobia, racism, prejudice, and stereotyping in different contexts, including topics such as Covid-19, religion and racism, information manipulation, and populism. The book, therefore, is a must-read for students, researchers, and scholars of political science, psychology, history, sociology, communications/media studies, diplomatic studies, and law in general, as well as ethnic and racial studies, American politics, global affairs, populism, and discrimination in particular.