The book presents both theoretical deliberations and practitioner cases of Holistic Flexibility. The development of systems thinking in OR/MS is described leading to the latest debates on the subject and the key pillars of Holistic Flexibility are discussed in detail. A range of case studies are presented that offer a firsthand experience of Holistic Flexibility in practice. Learnings are drawn to highlight the importance of a spiritual approach in management, an understanding which is used to further develop the conceptual lens of Holistic Flexibility since it was first introduced. This book presents a range of competencies required for systems practitioners to address and respond to complex situations in an interconnected world. A bold attempt to pragmatize systems thinking and systems practice, the ideas presented in this book weave a thread between the development of the discipline, current debates, and what lies ahead. It will be highly beneficial for OR/MS researchers and graduate students who are interested in systems thinking as well as researchers interested in connecting modern management thinking and Eastern mysticism.