in the Series provides a comprehensive and in-depth exploration of the SARS-CoV-2 virus and its impact on human health. Written by a team of expert contributors, the book covers various aspects of the virus, including its structure, lifecycle, and genomic replication. It delves into the epidemiology of COVID-19, comparing it with other related coronaviruses and discussing the concept of herd immunity. The structural biology of SARS-CoV-2 is examined, with a focus on techniques such as electron microscopy and cryo-electron tomography. The book also explores the biology of SARS-CoV-2 variants and their immune evasion strategies. Furthermore, it delves into the pathogenesis of COVID-19, examining its multiorgan manifestations and the long-term effects of the disease. The innate and adaptive immune responses to SARS-CoV-2 are discussed in detail, along with the role of B cells and T cells in the immune response. The volume concludes with a look at future insights and potential developments in the field. Accompanied by illustrative diagrams and visuals, this volume will serve as a valuable resource for researchers, healthcare professionals, and anyone interested in understanding the intricate details of SARS-CoV-2 and its impact on global health.