The VADE MECUM IN TRIBULACIONE was meant as an eschatological manual for the thirteen catastrophic years between its composition in December 1356 and the Thousand-Year Reign of Christ expected to begin in 1370. This manual, permeated by passion for clerical reform, was intended to give righteous Christians practical and spiritual advice on how to survive this period of tribulation. Likewise, it aimed to inform them about what to expect from the envoys of Satan, the Western and the Eastern Antichrists, but also from Christ’s warriors, the papal restorer and his secular assistant, the French-Roman Emperor. Moreover, it offered a brief outline of Christ’s Thousand-Year Reign and of Armageddon.