An estimated 21 million people are diagnosed each year with a major depressive disorder in the USA, Western Europe and Japan. The economic cost of depression and its impact on sufferers and those around them is enormous. There are numerous therapy choices available, which can be daunting for the clinician trying to achieve the best treatment regimen. Managing Depression in Clinical Practice provides a concise overview of the clinical manifestation, diagnosis and management of this debilitating condition. The book gives practical coverage of depression in special populations, the management of treatment non-response and long-term treatment. is intended as an accessible text for family practitioners and psychiatrists in training and in practice. It will also be of interest to specialist nurses and allied health professionals working in the field.