This book is the first to review in depth the neurobiological and clinical characteristics of memory and its disorders in neurodegenerative disease. It presents current information about memory disorders in Alzheimer's, Huntington's and Parkinson's diseases and in other neurological conditions such as progressive supranuclear palsy, Creutzfeld-Jacob disease and HIV-associated dementia. The contributors are among the most distinguished working in this field. They present the neuroanatomical and neurochemical basis of memory disorders in neurodegenerative disease, and review the contribution of neuroradiology and neuropathology to the understanding of memory and amnesia. The contributors discuss diagnosis, assessment and treatment issues, as well as ethical and legal considerations and topics of emerging interest such as the early detection of dementia.