provides a compendium of biomarkers based methodologies for respective health related fields and health related marker-specific biostatistical techniques. The book introduces correct and efficient testing mechanisms, including procedures based on bootstrap and permutation methods with the aim of making these techniques assessable to practical researchers. In the biostatistical aspect, it describes how to correctly state testing problems, but it also includes novel results, which have appeared in current statistical publications. In addition, the book discusses also modern applied statistical developments that consider data-driven techniques, including empirical likelihood methods and other simple and efficient methods to derive statistical tools for use in health related studies.