This book introduces the advances in synchromodal logistics and provides a framework to classify various optimisation problems in this field. It explores the application of this framework to solve a broad range of problems, such as problems with and without a central decision-maker, problems with and without full information, deterministic problems, problems coping with uncertainty, optimisation of a full network design problem. It covers theoretical constructs, such as discrete optimisation, robust optimisation, optimisation under uncertainty, multi-objective optimisation and agent based equilibrium models. Moreover, practical elaborated use cases are presented to deepen understanding. The book gives both researchers and practitioners a good overview of the field of synchromodal optimisation problems and offers the reader practical methods for modelling and problem-solving.