What it is: A powerful day to night antiwrinkle serum that includes the highest potency of Perricone MD's signature sciences. What it does: This serum is formulated with Dr. Perricone's next generation polyamide technology, encapsulated retinol and eggshell membrane to help visibly lift and improve skin plumpness, cushion, bounce and resiliency.Key ingredients:- Polyamine Growth Factor: an endogenous molecule that improves the feel of skin elasticity and helps promote the look of youthful, collagen-rich and visibly firmer skin by replenishing moisture- Encapsulated retinol: a stabilized form of retinol, this ultrapowerful, nonprescription vitamin A derivative replenishes the look of thin, collagen-depleted skin by accelerating surface skin exfoliation and renewal- Eggshell membrane: a thin, water-soluble layer that lines an eggshell helps support the skin's moisture barrier and provide skin with a youthful texture and radiance by improving the feel of elasticity over timeHow to use: After cleansing, massage onto your face and neck using gentle upward motions. Wait until fully absorbed and follow with your favorite moisturizer. Use morning and evening. 2 oz. Cruelty-free Made in the USA