During the COVID-19 pandemic, digital frontier technologies such as artificial intelligence and big data analytics, amongst others, have been mobilized to fight against the pandemic. But it is also important that digital technologies serve the needs of the Sustainable Development Goals. This report reviews the status of digital frontier technologies in the Asia-Pacific region. It stresses that the policy framework for the next generation of technology and innovation should focus on creating an enabling environment for digital frontier technologies to positively impact economy, society, and environment; and to reduce inequalities.