Responsible use of animals in research can be nothing but teamwork. The environment and professional experience of all involved stakeholders are the key for ensuring quality science, as well as animal and personnel welfare. Research animal care and use programs represent a complex system in which animals, legislation and good practices, facility personnel and researchers interact on a daily basis. Thoughtful planning from the first step ensures animal welfare and improves the quality of in vivo experimentation. This book addresses animal program managers, veterinarians, researchers and technicians working in research animal facilities. Chapter 18 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.