Turbulence characterises the current global scene. This book uses complementary theoretical approaches to understand and help prescribe policies to ‘re-frame’ the regional development problem in turbulent times. These approaches are: evolutionary complexity; evolutionary economic geography; emergence theory; and resilience theory. From below, they address the four major crises creating a ‘perfect storm’ for societies and economics involving: the climate change crisis; the energy crisis; the banking and financial crisis; and the global economic crisis.