The United States remains the preeminent global power of the 21st century, but faces significant challenges including emerging transnational threats, an unsustainable national economy, and declining ideological influence. Overcoming these challenges will require a fundamental reexamination of American culture and specific policy action by strategic leaders to (1) restore individual resilience, (2) repair a dysfunctional political culture, and (3) leverage a unifying national identity to thrive in an increasingly competitive global environment. Many policy decisions over the last decade have weakened American resilience and undermined trust in political institutions. Allowing further cultural decay risks a prolonged period of declining strategic relevance and eroding standards of living. Rebuilding American culture on the strong foundation of traditional American ideology and vibrant civil society will enable the United States to maintain a position of global leadership, forge new partnerships, and exploit new economic opportunities.