Volume 24, entitled
Targeted Metallo-Drugs: Design, Development, and Modes of Action,
of the series
Metal Ions in Life Sciences
(MILS), fosters inter-disciplinary research in the vibrant field of
Biological Inorganic Chemistry
. Inspired by the clinical success of cisplatin as a leading anticancer drug but mindful of the shortcomings associated with its use including dose-limiting toxic side effects and acquired or intrinsic drug resistance, scientists across the globe have been endeavoring to identify new metallo-drugs for therapeutic exploitation. This has led to innovative metallo-drug candidates that (i) enhance cancer cell selectivity, thus reducing toxic side effects, and/or (ii) possess new modes of action to improve efficacy and also target resistance pathways. This and more are captured in MILS- 24 which consists of 12 comprehensive, well-illustrated, and up to date chapters with over
1600
citations,
100
figures, and
10
tables with key contributions from
32
international experts from Europe, Asia, and North and South America. MILS- 24 not only keeps the scientific community abreast of latest developments, it also serves as an invaluable resource to stimulate further research on targeted metallo-drug design and development.
It covers anticancer, antimicrobial, antiviral, and other agents, such as those targeting tropical diseases and cyanide poisoning and radiometals in molecular imaging and therapy
It highlights recent metallo-drug developments targeting COVID-19
It features advanced spectroscopic methods and metallomics as important tools to elucidate the modes of actions of metallo-drugs