Defeat was looming for the South—as the Civil War continued, paths to possible victory were fast disappearing. Dr. Luke Pryor Blackburn, a Confederate physician and expert in infectious diseases, had an idea that might turn the tide: he would risk his own life and career to bring a yellow fever epidemic to the North. To carry out his mission, he would need some accomplices. Tracing the plans and movements of the conspirators, this thoroughly researched history describes in detail the yellow fever plot of 1864-1865.