An uninspired horror film by Edward Dein, this ragged story begins in darkest Africa and in the even darker psyche of a mentally deteriorating woman. June Talbot (Colleen Gray) goes on a trip to Africa with her husband Dr. Paul Talbot (Phillip Terry), only to discover that she is to be the trial balloon in one of his experiments on an anti-aging compound. Not willing to jump off into the unknown, the already unbalanced June kills her husband after she learns of a tribal ritual that will keep her youthful if she can obtain a hormone from the pineal gland of a human male. The problem is that she will revert back to a wrinkled woman unless she keeps replenishing her stock of the hormone. That, of course, leads to gruesome killings and ultimately, one disastrous mistake.