The volume contains papers from a seminar in Rome in 2016 that explored the nature and activity of the emergent Christian intellectual between the late first century and the early third century. The papers show that Hellenistic scholarly cultures were the milieu within which Christian modes of thinking developed. At the same time the essays show how Christian thinkers made use of the cultures of which they were part in distinctive ways, adapting existing traditions because of Christian beliefs and needs. The figures studied include Papias from the early part of the second-century, Tatian, Irenaeus, and Clement of Alexandria from the later second century. One paper on Eusebius of Caesarea explores the Christian adaptation of Hellenistic scholarly methods of commentary. Christian figures are studied in the light of debates within Classics and Jewish studies.