We live in a world of intense social transformation, economic uncertainty, cultural innovations, and political turmoil. Established understandings of issues of well-being, development, democratisation, progress, and sustainability are being rethought both in academic scholarship and through everyday practice, organisation and mobilisation. The contributors to this handbook provide state-of-the-art introductions to current thinking on central conceptual and methodological approaches to the analysis of the transformations shaping economies, polities, and societies. Topics covered include social movements, NGOs, the changing nature of the state, environmental politics, human rights, anti-globalism, pandemic emergencies, post-Brexit politics, the politics of resilience, new technologies, and the proliferation of progressive and reactionary forms of identity politics. Drawing on disciplines including anthropology, human geography, political sociology, and development studies, this is a comprehensive and authoritative introduction to researching key issues raised by the challenge of making sense of the twenty-first century futures.