The remnants of humanity flee to the coldest regions of the Earth, where they build walls to protect themselves from the wandering infected--the husks. Armed with her father's shamanic drum, Bree settles in Tomsk, the largest city in Siberia, where she uses the beats of the drum to draw these husks to her; the steady beats mirroring the heartbeats of their hosts. Arrested by the city's patrol guards, she and her neighbour, Tyler, who is working on a cure, must convince the council that his serum can neutralise the parasites, eradicating the threat on humanity. But the council aren't ready to listen.