The COVID-19 pandemic disrupted some lives more than others. While more than half the world’s population experienced physical restrictions in the wake of the virus, reveals how the international response placed disparate burdens on exploited communities across the globe. Contributors from six continents situate the pandemic within a highly connected yet exceedingly unequal world marked by fragmented communities, austere economies, and unstable governments. Ambitious in its scope, insists that medical anthropology must be part of any future efforts to build a new post-pandemic world.